Patent · US Active

Method for identifying biologically active oligonucleotides capable of modulating the immune system

US9157919B2 · kind B2 · utility

0Cited by

0References

16Claims

0Family size

Assignee

Index Pharmaceuticals AB · SE

Inventors

Arezou Zargari · Solna, SE
Nicolai Kouznetzov · Järfälla, SE
Charlotte Admyre · Handen, SE
Petra Von Stein · Spånga, SE
Oliver Von Stein · Upplands Väsby, SE

Key dates

Filing date	Dec 20, 2011
Grant date	Oct 13, 2015
Priority date	—
Expiry date	Dec 20, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/11
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to methods of identifying oligonucleotides capable of modulating the immune system in a mammalian subject, comprising analysis of which tertiary structural type said oligonucleotide adopts, in phosphate-buffered saline solution. Further, the invention provides oligonucleotides identifiable by the methods of the invention and to their use in methods of treating diseases, such as inflammatory diseases, autoimmune diseases, infectious diseases, neurodegenerative diseases and cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.