Specificity of analyte detection in etalons

US9161714B2 · kind B2 · utility

Assignee

• Palo Alto Research Center Incorporated · US

Inventors

• Joerg Martini · San Francisco, US
• Richard H. Bruce · Los Altos, US
• Francisco E. Torres · San Jose, US
• Peter Kiesel · Palo Alto, US
• Michael I. Recht · Redwood City, US
• Jeffrey N. Roe · San Ramon, US

Key dates

• Filing date: Aug 21, 2008
• Grant date: Oct 20, 2015
• Expiry date: Apr 26, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/359
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.