Patent · US Active

Adhesive compositions for the treatment of xerostomia

US9161909B2 · kind B2 · utility

2Cited by

13References

18Claims

0Family size

Assignee

Axiomedic Ltd. · GI

Inventors

Abraham J. Domb · Beer Sheva, IL
Benny Brama · Raanana, IL
Boaz Mizrahi · Haifa, IL

Key dates

Filing date	Apr 9, 2010
Grant date	Oct 20, 2015
Priority date	—
Expiry date	Apr 10, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compositions for the treatment of xerostomia, and methods of making and using thereof are disclosed herein. The compositions are typically in the form of a film or tablet, such as a double layer sticker tablet. The compositions adhere to a buccal surface or mucosal surface in the oral cavity for at least 15 minutes, preferably for at least 30 minutes. The compositions themselves are able to increase the levels of saliva in the mouth without the need for active agents, such sialogogic agents. The compositions optionally contain a non-lipid lubricant, a flavoring agent, and/or a buffering agent. The composition is generally effective at treating or ameliorating the effects of xerostomia for a time period ranging from at least 30 minutes up to eight hours following administration to the buccal or oral mucosa.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.