Sample filtration assembly
US9162186B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 14, 2012 |
| Grant date | Oct 20, 2015 |
| Priority date | — |
| Expiry date | Jun 4, 2034 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2313/24
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention provides a filtration assembly in the form of a disposable cartridge. A key feature of the invention is a filtration chamber having a porous membrane also referred to as a filter, a sample inlet to the filtration chamber, and an outlet for outflow of the fraction of sample that does not penetrate the membrane. The membrane can be used in any configuration, for example a hollow fiber. The fraction of sample that penetrates the membrane is referred to as the filtrate, and the fraction that does not penetrate the membrane is referred to as the retentate or concentrate. Some uses of the cartridge are to prepare plasma from blood, and to prepare a plasma ultra-filtrate from plasma, without the need for centrifugation. Many therapeutic drugs are highly protein bound, and a plasma ultra-filtrate is sometimes required to measure the unbound biologically active drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.