Biomarkers to identify HIV-specific T-cell subsets

US9164094B2 · kind B2 · utility

Assignees

• DANA-FARBER CANCER INSTITUTE, INC. · US
• The Brigham and Women's Hospital, Inc. · US
• The General Hospital Corporation · US

Inventors

• W. Nicholas Haining · Newton, US
• Benjamin Ebert · Brookline, US
• Bruce Walker · Nahant, US

Key dates

• Filing date: Apr 20, 2012
• Grant date: Oct 20, 2015
• Expiry date: Apr 20, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/56
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention relates to expression profiles of HIV-specific T-cells and their methods of use, including but not limited to treatment of HIV, increasing T-cell function and/or survival in HIV infected subjects, monitoring HIV disease progression and classifying HIV infected subjects as controllers or chronic progressors.