Formulations targeting IGFBP7 for diagnosis and therapy of cancer
US9164097B2 · kind B2 · utility
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1References
21Claims
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Key dates
| Filing date | Oct 14, 2009 |
| Grant date | Oct 20, 2015 |
| Priority date | — |
| Expiry date | Nov 19, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4745
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to antibodies or fragments thereof specific for insulin-like growth factor binding protein-7 (IGFBP7). A method of raising anti-IGFBP7 single domain antibodies is also disclosed and specific antibody clones are described, along with their binding characteristics. The anti-IGFBP7 antibodies may be useful as diagnostic tools for detecting neoplastic diseases involving tumor angiogenesis, and a variety of other angiogenesis associated diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.