Multi-encapsulated microspheres made with oxidized cellulose for in-situ reactions

US9168227B2 · kind B2 · utility

Assignee

• Covidien LP · US

Inventors

• Phillip Blaskovich · Salem, US
• Clifford J. Herman · Chesterfield, US
• Gary A. Nichols · Hazelwood, US
• Rachit Ohri · Framingham, US
• Lan Pham · Nashua, US

Key dates

• Filing date: Sep 12, 2013
• Grant date: Oct 27, 2015
• Expiry date: Sep 12, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K47/38
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A microsphere and methods for forming the same are disclosed. The microsphere includes modified cellulose and at least one first microsphere disposed within a multi-encapsulating microsphere, the at least one first microsphere comprising at least one first hydrogel precursor; and at least one second microsphere disposed within the multi-encapsulating microsphere, the at least one second microsphere comprising at least one second hydrogel precursor cross-linkable with the at least one first hydrogel precursor upon degradation of the at least one first microsphere and the at least one second microsphere.