Beta carboline derivatives useful in the treatment of proliferative disorders

US9168247B2 · kind B2 · utility

Assignees

• FACULTES UNIVERSITAIRES NOTRE DAME DE LA PAIX · BE
• UNIVERSITÉ LIBRE DE BRUXELLES · BE

Inventors

• Raphaël FRÉDÉRICK · Godinne, BE
• Bernard Masereel · Fize-Fontaine, BE
• Jeremy Reniers · Biercée, BE
• Johan Wouters · Beez, BE
• Celine Bruyere · Forest, BE
• Robert Kiss · South San Francisco, US
• Céline Anne Marie Michelle Meinguet · Ciney, BE
• Veronique Mathieu · Wavre, BE

Key dates

• Filing date: Jun 24, 2011
• Grant date: Oct 27, 2015
• Expiry date: Jun 24, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides novel beta-carboline derivatives of formulae (Ia) and (Ib) useful in the treatment of proliferative disorders including cancer, intermediates used in their preparation, processes for preparing the same and uses thereof.