Patent · US Active

Artificial nucleic acids

US9169256B2 · kind B2 · utility

1Cited by
0References
5Claims
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Key dates

Filing dateMar 13, 2014
Grant dateOct 27, 2015
Priority date
Expiry dateMay 9, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65616
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Artificial nucleosides including 2-methyl-nucleobase-substituted butane-1,3-diol nucleosides are disclosed. Four different stereoisomers of such nucleosides are possible. Oligonucleotides made up of the artificial nucleosides form homoduplexes of greater stability than DNA duplexes and have a reduced ability to hybridize to DNA or RNA.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.