Process for preparing pharmaceutical compounds and intermediate compounds
US9169265B2 · kind B2 · utility
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3References
28Claims
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Key dates
| Filing date | Dec 21, 2010 |
| Grant date | Oct 27, 2015 |
| Priority date | — |
| Expiry date | Feb 12, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The object of the present invention is a process for preparing the 2-acetoxi-5-(2-fluor-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-thieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts from crystalline 5-trityl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine of the formula (VI).Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.