Thiadiazole-substituted arylamides as P2X3 and P2X2/3 antagonists
US9173861B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jan 26, 2012 |
| Grant date | Nov 3, 2015 |
| Priority date | — |
| Expiry date | Jan 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.