Mediators of hedgehog signaling pathways, compositions and uses related thereto
US9173869B2 · kind B2 · utility
4Cited by
9References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 2010 |
| Grant date | Nov 3, 2015 |
| Priority date | — |
| Expiry date | Jun 22, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/91
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.