Vitamin D-ghrelin conjugates

US9173950B2 · kind B2 · utility

Assignee

• Extend Biosciences, Inc. · US

Inventors

• Tarik Soliman · Chester Springs, US
• Laura M. Hales · Cambridge, US
• Howard Sard · Arlington, US
• Mukkanti Amere · Woburn, US

Key dates

• Filing date: Nov 15, 2014
• Grant date: Nov 3, 2015
• Expiry date: Nov 15, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides carriers that enhance the absorption, half-life or bioavailability of Ghrelin peptides. The carriers comprise targeting groups that bind the Vitamin D Binding protein (DBP), conjugation groups for coupling the targeting groups to the therapeutic compounds, and optionally scaffolding moieties.