Patent · US Active

Prodrugs containing an aromatic amine connected by an amido bond to a linker

US9173953B2 · kind B2 · utility

17Cited by

1References

20Claims

0Family size

Assignee

ASCENDIS PHARMA A/S · DK

Inventors

Harald Rau · Würzburg, DE
Julia Baron · Heidelberg, DE
Ulrich Hersel · Heidelberg, DE
Mathias Krusch · Hirschhorn, DE

Key dates

Filing date	Jul 30, 2010
Grant date	Nov 3, 2015
Priority date	—
Expiry date	Nov 11, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/24
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising a drug linker conjugate D-L, wherein an aromatic amine containing biologically active moiety is connected (bound) by an amido bound to a linker. The invention also relates to pharmaceutical compositions comprising said prodrugs and their use as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.