Diagnostic and treatment for chronic and acute phase myeloid leukemia
US9173963B2 · kind B2 · utility
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Key dates
| Filing date | May 14, 2010 |
| Grant date | Nov 3, 2015 |
| Priority date | — |
| Expiry date | May 14, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are methods of predicting responsiveness of a cancer cell to a tyrosine kinase inhibitor, and methods of predicting the risk of progression of a cancer cell to a more aggressive form. Also provided are methods of reducing proliferation or promoting differentiation of a cancer cell having reduced level of Numb or increased level of Msi. Further disclosed are methods of treating a mammalian subject having cancer and methods of assessing an agent for chemotherapeutic potential.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.