Production of conjugates
US9176125B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 12, 2008 |
| Grant date | Nov 3, 2015 |
| Priority date | — |
| Expiry date | Jun 12, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/532
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a method for indirectly coupling a small molecule ligand to a molecule to be labelled with the ligand, the method comprising the step of: contacting a scaffold molecule, to which is attached at least one small molecule ligand, with the molecule to be labelled, the scaffold molecule having at least one group which is reactive towards a receiver moiety present or formed in situ on the molecule to be labelled, so as to forma bond between the scaffold molecule and the molecule to be labelled, thereby indirectly coupling the small molecule ligand to the molecule to be labelled.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.