Flexible nonlinear laser scanning microscope for noninvasive three-dimensional detection

US9176309B2 · kind B2 · utility

Assignee

• JenLab GmbH · DE

Inventors

• Karsten Koenig · Riegelsberg, DE
• Martin WEINIGEL · Jena, DE

Key dates

• Filing date: Oct 5, 2012
• Grant date: Nov 3, 2015
• Expiry date: May 24, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01J2001/4238
• WIPO field: Optics
• WIPO sector: Instruments

Abstract

A nonlinear laser scanning microscope for flexible, noninvasive three-dimensional detection comprising a measuring head which is flexibly connected to at least one radiation source by transmission optics and can be freely positioned in space, at least one controllable tilt mirror is arranged for aligning the excitation beam in order to keep the excitation beam concentric to an aperture-limited optical element of the measuring head, a test beam which is coupled out of the excitation beam onto a spatially resolving photodetector for monitoring the center alignment of the test beam as a conjugate position to the target position of the excitation beam and directional stabilizing the excitation beam by a control unit of the tilt mirror depending on a determined deviation.