Compositions and methods for topical application and transdermal delivery of botulinum toxins
US9180081B2 · kind B2 · utility
15Cited by
75References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 3, 2006 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Oct 9, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/24069
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Improved formulations for transdermal delivery of botulinum toxin are disclosed. The formulations include, for example, botulinum toxin non-covalently associated with a positively charged backbone having branching or efficiency groups. The formulations also include a partitioning agent, oligo-bridge, or polyanion bridge, and may optionally contain a viscosity modifying agent. The formulations are designed for topical application onto the skin of a patient and may be used to treat wrinkles, hyperhidrosis, and other health-related problems. Kits for administration are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.