Patent · US Active

Composite bone graft substitute cement and articles produced therefrom

US9180224B2 · kind B2 · utility

18Cited by
219References
77Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 11, 2010
Grant dateNov 10, 2015
Priority date
Expiry dateApr 12, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L2430/02
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.