Intermediates for macrocyclic compounds
US9181298B2 · kind B2 · utility
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3Claims
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Assignee
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Key dates
| Filing date | Nov 19, 2008 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Apr 19, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0827
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates:wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.