Patent · US Active

Crosslinked polyvinylamine, polyallylamine, and polyethyleneimine for use as bile acid sequestrants

US9181364B2 · kind B2 · utility

2Cited by

15References

19Claims

0Family size

Assignee

Relypsa, Inc. · US

Inventors

Jordan Kopping · Redding, US
Kalpesh Biyani · Fremont, US
Eric Connor · Los Gatos, US
Scott Hecker · Del Mar, US
Inez Lees · Mountain View, US
Grace May Huynh · San Francisco, US
Faleh Salaymeh · Sunnyvale, US
Hongmin Zhang · Santa Clara, US
David E. Bergbreiter · College Station, US
Paul Mansky · San Francisco, US
YongQi Mu · Los Altos, US
Michael J. Cope · Berkeley, US
Elizabeth Goka · San Jose, US
Angela Lee · San Jose, US
Deidre Madsen · Sunnyvale, US
Jun Shao · Fremont, US

Key dates

Filing date	Feb 24, 2011
Grant date	Nov 10, 2015
Priority date	—
Expiry date	Apr 15, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08F232/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a crosslinked amine and amide polymers effective for binding and removing bile salts from the gastrointestinal tract. These bile acid binding polymers or pharmaceutical compositions thereof can be administered to subjects to treat various conditions, including hypercholesteremia, diabetes, pruritis, irritable bowel syndrome-diarrhea (IBS-D), bile acid malabsorption, and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.