Cell systems and methods for improving fatty acid synthesis by expression of dehydrogenases
US9181568B2 · kind B2 · utility
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20References
42Claims
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Key dates
| Filing date | Apr 23, 2012 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Jan 2, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y102/01
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to methods for producing lipids such as fatty acid products in recombinant host cells engineered to express a non-native gene encoding a dehydrogenase. The recombinant microorganisms are able to proliferate at a higher rate as compared with microorganisms that do not express a non-native dehydrogenase gene, and cultures of microorganisms that are engineered for lipid production and that express a non-native dehydrogenase produce more lipid than cultures of control microorganisms that do not include a non-native dehydrogenase gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.