Polynucleotide mapping and sequencing
US9181578B2 · kind B2 · utility
6Cited by
39References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2009 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Oct 25, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides methods of obtaining structural information about a biopolymer sample. The methods include labeling portions of a biopolymer, such as DNA or RNA, linearizing the biopolymer in some cases, and determining the distance between the labels. The user can then compare different samples' between-label distances to qualitatively compare different samples and to assay a given sample for additions or deletions of nucleotides in the regions flanked by the labels. The methods also permit sequencing of biopolymers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.