Methods for cancer detection, diagnosis and prognosis
US9182387B2 · kind B2 · utility
13Cited by
4References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 6, 2013 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Sep 6, 2033 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25375
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.