Method of screening by using conformation sensitive peptides
US9182408B2 · kind B2 · utility
0Cited by
5References
22Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 16, 2005 |
| Grant date | Nov 10, 2015 |
| Priority date | — |
| Expiry date | Feb 25, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6845
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to a screening technology that allows the isolation of peptides able to bind to target protein, the binding of which being sensitive to the protein conformation. The invention further provides a method to identify compounds that specifically and precisely modify the protein conformation and its biological activity. Finally, the invention relates to certain peptides obtained by the method of screening of the present invention and their use as therapeutic agent for the prevention or treatment of diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.