Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients

US9186295B2 · kind B2 · utility

Assignee

• CORNING INCORPORATED · US

Inventors

• Wendell Porter Weeks · Corning, US
• Robert Anthony Schaut · Corning, US
• Steven Edward DeMartino · Corning, US
• John Stephen Peanasky · Big Flats, US

Key dates

• Filing date: Oct 25, 2012
• Grant date: Nov 17, 2015
• Expiry date: May 2, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/131
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LANTUS (insulin glargine [rDNA]), LOVENOX (Enoxaparin), PENTACT-HIB (Hemophilus influenzae type b polysaccharide conjugated to tetanus protein, diphtheria, tetanus, pertussis and inactivated poliovirus vaccines) or FLUZONE or VAXIGRIP (influenza virus vaccine).