Patent · US Active

Formulations of deoxycholic acid and salts thereof

US9186364B2 · kind B2 · utility

8Cited by

64References

9Claims

0Family size

Assignee

Kythera Biopharmaceuticals, Inc. · US

Inventors

Robert Emil Hodge · McPherson, US
Jeffrey Douglas Webster · Thousand Oaks, US

Key dates

Filing date	Jan 3, 2013
Grant date	Nov 17, 2015
Priority date	—
Expiry date	Jan 3, 2033

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application is directed to an aqueous pharmaceutical formulation comprising less than about 5% w/v sodium deoxycholate maintained at a pH sufficient to substantially inhibit precipitation of the sodium deoxycholate. Also disclosed herein, are methods for inhibiting precipitation of sodium deoxycholate in an aqueous solution comprising less than about 5% w/v of sodium deoxycholate, said method comprising maintaining pH of the solution of from at least about 8.0 to about 8.5.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.