Patent · US Active

Methods and uses of TIE2 binding and/or activating agents

US9186390B2 · kind B2 · utility

2Cited by

1References

26Claims

0Family size

Assignee

SUNNYBROOK HEALTH SCIENCES CENTRE · CA

Inventors

Paul Van Slyke · Colorado Springs, US
Daniel Dumont · Fontainebleau, FR

Key dates

Filing date	Apr 28, 2011
Grant date	Nov 17, 2015
Priority date	—
Expiry date	Jun 6, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/475
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides methods and uses of Tie2 binding and/or activating agents. In particular, the present disclosure provides methods and uses for inhibiting the expansion of colony forming unit-granulocytes, reducing eosinophils and/or basophils, for treating allergic disease or response or eosinophil/basophil associated condition and for reducing inflammatory cytokine and/or chemokine levels.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.