Patent · US Active

TRPV4 antagonists

US9187464B2 · kind B2 · utility

2Cited by
0References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 15, 2012
Grant dateNov 17, 2015
Priority date
Expiry dateJun 15, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65583
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to spirocarbamate compounds of Formula (I) in which R1, (R2)Y, R3, R4, X and A have the meanings given in the specification. The invention further provides pharmaceutical compositions containing the compounds or pharmaceutically acceptable salts thereof and relates to their use of these compounds as TRPV4 antagonists in treating or preventing conditions associated with TRPV4 imbalance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.