Bicyclic pyridazine compounds as Pim inhibitors
US9187486B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Apr 19, 2012 |
| Grant date | Nov 17, 2015 |
| Priority date | — |
| Expiry date | May 17, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to bicyclic compounds of formulas I and I′, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pim kinase related conditions and diseases, preferably cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.