Antiangiogenic brassinosteroid compounds
US9187518B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 14, 2012 |
| Grant date | Nov 17, 2015 |
| Priority date | — |
| Expiry date | Dec 14, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a solid tumor in a mammal by inhibiting angiogenesis, including administering to the mammal which has a solid tumor selected from the group consisting of breast carcinoma, lung carcinoma, prostate carcinoma, colon carcinoma, ovarian carcinoma, neuroblastoma, central nervous system tumor, multiform glioblastoma and melanoma; a composition including brassinosteroids of general formula (I)wherein can be a single or double bond and the configurations of carbon atoms C22 and C23 respectively linked to the substituents HO are S for both carbon atoms and a pharmaceutically acceptable additive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.