Patent · US Active

Polypeptide derived from protein A and able to bind PDGF

US9187535B2 · kind B2 · utility

11Cited by

6References

44Claims

0Family size

Assignee

AFFIBODY AB · SE

Inventors

Malin Lindborg · Boo, SE
Elin Gunneriusson · Hallsberg, SE
Christofer Lendel · Älta, SE

Key dates

Filing date	Dec 17, 2008
Grant date	Nov 17, 2015
Priority date	—
Expiry date	Jun 12, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides a platelet derived growth factor receptor beta (PDGF-Rβ) binding polypeptide, comprising a platelet derived growth factor receptor beta binding motif, PBM, which motif consists of an amino acid sequence as defined herein, wherein the PDGF-Rβ-binding polypeptide binds to PDGF-Rβ such that the KD value of the interaction is at most 1×10−6 M. Also provided are methods and uses of said polypeptide in treatment and diagnosis of PDGF-Rβ-related conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.