Patent · US Active

Optimized non-canonical zinc finger proteins

US9187758B2 · kind B2 · utility

30Cited by

11References

18Claims

0Family size

Assignees

Sangamo Biosciences, Inc. · US
DOW AGROSCIENCES LLC · US

Inventors

Qihua C. Cai · Westfield, US
Vipula Shukla · Indianapolis, US
Joseph F. Petolino · Zionsville, US
Lisa W. Baker · Carmel, US
Robbi J. Garrison · Merrillville, US
Ryan C. Blue · Fishers, US
Jon C. Mitchell · West Lafayette, US
Nicole L. Arnold · Carmel, US
Sarah E. Worden · Fillmore, US
Jeffrey C. Miller · Pleasanton, US
Fyodor Urnov · Richmond, US

Key dates

Filing date	Dec 13, 2007
Grant date	Nov 17, 2015
Priority date	—
Expiry date	Jul 13, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/81
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.