Methods for producing methionine by culturing a microorganism modified to enhance production of cysteine
US9187775B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jan 9, 2013 |
| Grant date | Nov 17, 2015 |
| Priority date | — |
| Expiry date | Oct 10, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P13/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of producing methionine, derivatives or precursors thereof includes culturing a modified microorganism in a culture medium comprising a source of carbon and a source of sulfur; and recovering methionine from the culture medium, wherein said modified microorganism has an increased expression of cysE gene encoding serine acetyltransferase, metH gene encoding methionine synthase and metF gene encoding 5,10-methylenetetrahydrofolate reductase compared to expression of the cysE, metH and metF genes in an unmodified microorganism.
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