Patent · US Active

Methods and devices for in situ nucleic acid synthesis

US9187777B2 · kind B2 · utility

76Cited by

37References

26Claims

0Family size

Assignee

Gen9, Inc. · US

Inventors

Joseph M. Jacobson · Newton, US
Senthil Ramu · Boston, US
Daniel Schindler · Newton, US

Key dates

Filing date	May 26, 2011
Grant date	Nov 17, 2015
Priority date	—
Expiry date	Nov 27, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P19/34
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed are compositions, methods and devices for the in situ synthesis of nucleic acids. In an exemplary embodiment, a support-bound oligonucleotide is elongated by addition of one or more nucleotides by hybridization of a partially double-stranded oligonucleotide, ligation and removal of unwanted nucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.