Patent · US Active

Esters and malonates of SATE prodrugs

US9192621B2 · kind B2 · utility

29Cited by
141References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 26, 2013
Grant dateNov 24, 2015
Priority date
Expiry dateSep 26, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, provided herein are compounds according to Formula 1001:or a pharmaceutically acceptable salt, solvate, stereoisomeric form, tautomeric form or polymorphic form thereof, wherein Base, Y, Z, A, RC and RD are as described herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.