Patent · US Active

Allografts combined with tissue derived stem cells for bone healing

US9192695B2 · kind B2 · utility

42Cited by
55References
64Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 4, 2009
Grant dateNov 24, 2015
Priority date
Expiry dateFeb 24, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2533/90
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There is disclosed a method of combining mesenchymal stem cells (MSCs) with a bone substrate. In an embodiment, the method includes obtaining tissue having MSCs together with unwanted cells. The tissue is digested to form a cell suspension having MSCs and unwanted cells. The cell suspension is added to the substrate and the MSCs are allowed to adhere. The substrate is rinsed to remove unwanted cells. In an embodiment, there is disclosed an allograft product including a combination of MSCs with a bone substrate made according to the described method. Other embodiments are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.