Induction of highly specific antibodies to a hapten but not to a carrier peptide by immunization

US9193739B2 · kind B2 · utility

Assignees

• The United States of America as represented by the Secretary of the Army · US
• The United States of America as Represented by the Secretary, Dept. of Health and Human Services · US

Inventors

• Carl R. Alving · Bethesda, US
• Gary R. Matyas · Olney, US
• Arthur E. Jacobson · Rockville, US
• Fuying Li · Rockville, US
• Malliga Iyer · Germantown, US
• Kenner C. Rice · Bethesda, US
• Kejun Cheng · Potomac, US
• Alexander V. Mayorov · Perm, RU

Key dates

• Filing date: Feb 8, 2013
• Grant date: Nov 24, 2015
• Expiry date: Feb 8, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/76
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

In this application is described a composition and method for inducing in a subject anti-hapten antibodies without inducing antibodies to the carrier protein. Kits for designing and making compositions with desired haptens are also described.