Pegylated analogue protein or canine urate oxidase, preparation method and use thereof
US9193967B2 · kind B2 · utility
1Cited by
3References
13Claims
0Family size
Inventors
Key dates
| Filing date | Feb 14, 2012 |
| Grant date | Nov 24, 2015 |
| Priority date | — |
| Expiry date | Feb 14, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are a PEGylated analogue protein of canine urate oxidase, preparation method and use thereof. The analogue protein of canine urate oxidase is a canine urate oxidase, or a chimeric protein comprising part of the amino acid sequence of a canine urate oxidase and part of the amino acid sequence of a human urate oxidase, or a mutant protein thereof. The PEGylated analogue protein of canine urate oxidase and pharmaceutical compositions thereof according to the present invention can be used for the prevention and/or treatment of hyperuricemia and chronic gout.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.