Patent · US Active

PRPK-TPRKB modulators and uses thereof

US9193989B2 · kind B2 · utility

0Cited by

0References

13Claims

0Family size

Assignee

Taiho Pharmaceutical Co., Ltd. · JP

Inventors

Eun Sun Park · Arlington, US
Henry Efrem Pelish · Newton, US
Astrid Clarke · Andover, US
Grace L. Williams · Waltham, US
Maria Paola Castaldi · Brookline, US
Alexander Arefolov · Newton, US
Jennifer E. Ring · Needham, US
Matthew D. Shair · Lexington, US
Randall W. King · Newton, US

Key dates

Filing date	Jun 17, 2011
Grant date	Nov 24, 2015
Priority date	—
Expiry date	Dec 14, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides methods of identifying an agent that modulates PRPK, TPRKB, OSGEP, LAGE3 and its homologs, PRPK/TPRKB complex, and/or KEOPS complex. The present invention also provides compositions of such agents and methods of treating a disease, disorder, or condition associated with PRPK, TPRKB, OSGEP, LAGE3 and its homologs family (CT antigens), PRPK/TPRKB complex, and/or KEOPS complex using such an agent or composition.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.