Mutants for the preparation of D-amino acids

US9194009B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Oliver May · Frankfurt, DE
• Stefan Buchholz · Hanau, DE
• Michael Schwarm · Alzenau, DE
• Karlheinz Drauz · Alzenau, DE
• Robert Turner · Aurora, US
• Ian Fotheringham · Edinburgh, GB

Key dates

• Filing date: Jan 21, 2009
• Grant date: Nov 24, 2015
• Expiry date: Jul 6, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/19
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Escherichia. coli mutants which can be used for the synthesis of D-amino acids, and to such a process. The mutants are distinguished by deficiencies in particular enzymes which break down D-amino acids and include those which produce D-amino acids via the carbamoylase/hydantoinase route.