N-substituted benzenepropanamide or benzenepropenamide derivatives for use in the treatment of pain and inflammation
US9199917B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Oct 7, 2014 |
| Grant date | Dec 1, 2015 |
| Priority date | — |
| Expiry date | Oct 7, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F3/003
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula (I) in which: the dotted line represents a single or a double bond; and R5 and R5′ are independently —H, —OH or —OR6, where R6 is a linear or branched C1-C4 alkyl; X is -0-, —CH2O—, —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is an integer of O or 1; and n is an integer of 0-50. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.