Fibronectin type III domain based scaffold compositions, methods and uses
US9200059B2 · kind B2 · utility
6Cited by
15References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 27, 2012 |
| Grant date | Dec 1, 2015 |
| Priority date | — |
| Expiry date | Mar 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B50/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.