Particle capture devices and methods of use thereof
US9201060B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 11, 2009 |
| Grant date | Dec 1, 2015 |
| Priority date | — |
| Expiry date | Sep 5, 2032 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0424
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a device and methods of use thereof in microscale particle capturing and particle pairing. This invention provides particle patterning device, which mechanically traps individual particles within first chambers of capture units, transfer the particles to second chambers of opposing capture units, and traps a second type of particle in the same second chamber. The device and methods allow for high yield assaying of trapped cells, high yield fusion of trapped, paired cells, for controlled binding of particles to cells and for specific chemical reactions between particle interfaces and particle contents. The device and method provide means of identification of the particle population and a facile route to particle collection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.