Inhibitors of anaphase promoting complex activity
US9205069B2 · kind B2 · utility
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1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2010 |
| Grant date | Dec 8, 2015 |
| Priority date | — |
| Expiry date | Jun 20, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides an anti-proliferative composition comprising a non-peptide analog of the C-terminal isoleucine-arginine (IR) tail motif of an activator of an anaphase promoting complex (APC). The invention further provides methods of inhibiting the ubiquitination activity of the APC by administering compositions of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.