Layer processing for pharmaceuticals

US9205089B2 · kind B2 · utility

Assignee

• Massachusetts Institute of Technology · US

Inventors

• Bernhardt Levy Trout · Lexington, US
• Trevor Alan Hatton · Sudbury, US
• Emily Chang · Edison, US
• James M B Evans · Sudbury, US
• Salvatore Mascia · Boston, US
• Won-Jong Kim · Tucson, US
• Ryan Richard Slaughter · Riverside, US
• Yi Du · Flemington, US
• Himanshu Hemant Dhamankar · Wilmington, US
• Keith M. Forward · Somerville, US
• Gregory C. Rutledge · Newton, US
• Mao Wang · Baoshan, TW
• Allan S. Myerson · Brooklyn, US
• Blair Kathryn Brettmann · Cambridge, US
• Nikhil Padhye · Cambridge, US
• Jung-Hoon Chun · Suwon-si, KR

Key dates

• Filing date: Apr 27, 2012
• Grant date: Dec 8, 2015
• Expiry date: Jun 19, 2033

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T156/1051
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.