Process for the preparation of sunitinib and its acid addition salts thereof
US9206163B2 · kind B2 · utility
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4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 2013 |
| Grant date | Dec 8, 2015 |
| Priority date | — |
| Expiry date | Mar 22, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/245
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to an improved process for the preparation of Sunitinb. The process involves the activation of 5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene) methyl)-2,4-dimethyl-1 H-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group. The present invention also relates to novel acid addition salts of Sunitinb and preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.