Dihydrothienopyrimidines

US9206195B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Kai Gerlach · Biberach, DE
• Niklas Heine · Eberhardzell, DE
• Scott Hobson · Mittelbiberach, DE
• Christoph Hoenke · Ingelheim am Rhein, DE
• Alexander Weber · Biberach an der Riß, DE

Key dates

• Filing date: Jul 27, 2012
• Grant date: Dec 8, 2015
• Expiry date: Aug 9, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to dihydrothienopyrimidines, their use as modulators of γ-secretase and to pharmaceutical compositions containing said compounds. In particular, the present invention relates to compounds which interfere with γ-secretase and/or its substrate and therefore modulate the formation of Aβ peptides.