Methods for pathogen detection and disease treatment

US9206213B2 · kind B2 · utility

Assignee

• Bangor University · GB

Inventors

• Mark Stephen Baird · Blaenau Ffestiniog, GB
• Juma'a Raheem Najeem Al Dulayymi · Blaenau Ffestiniog, GB
• Johan Grooten · Evergem, BE
• Seppe Vander Beken · Evergem, BE
• Maximilliano Maza-Inglesias · Bangor, GB

Key dates

• Filing date: Dec 9, 2013
• Grant date: Dec 8, 2015
• Expiry date: Jan 7, 2034

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/5695
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of preparing a compound of formula (III):(M)x-(S)y-(M′)z  (III)wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M′ is independently a mycolic acid residue including a β-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each β-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.