Bioreactor, devices, systems and methods

US9206383B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Gordana Vunjak-Novakovic · New York, US
• Warren Grayson · Reisterstown, US
• Qun Wan · New York, US
• Donald Freytes · Pittsburgh, US
• Amandine Godier-Furnémont · Franklin Lakes, US
• Nina Tandon · New York, US
• Keith Yeager · Jersey City, US
• George Eng · Boston, US
• Sarindr Bhumiratana · New York, US
• Robert Maidhof · Elmont, US

Key dates

• Filing date: Dec 6, 2010
• Grant date: Dec 8, 2015
• Expiry date: Apr 27, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12M41/48
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed are bioreactor devices, systems and methods. A bioreactor system can include one or more bioreactor modules that can be individually controllable and identifiable. A bioreactor module can be connected to one or more functional modules such as a pump module, a stimulation signal generation module, a motor module, a mechanical transmission module, a gas exchange module, a temperature module, a humidity module and/or a CO2 module, among others. The bioreactor and functional modules can include standard or universal connectors to facilitate connection and movement of modules. The bioreactor system can be controlled and/or monitored by a controller that can individually identify and control each connected module and that can be adapted to collect signal data from sensors embedded in any of the modules.